If you must discuss this on a biological, scientific level, A.E. Wilder Smith's books can be a huge benefit to help understand the fallacies, and benefits of science from a Christian point of view.
However, if you engage someone on an intellectual level, and convince them intellectually of a truth, they will only be as convinced as your argument allows them to be. Apologetics are better for people whom have already given their lives to Christ. The beginning of faith is having a collision with God, not understanding the collisions of molecules.
Believe me.
Share Christs love, let them see your faith, let them see Christ in you, and always center your evangelism around the cross and resurrection of Christ. The gospel itself is the power of God unto salvation. We need to remember this. Have faith in the gospel being able to convince someone of the truth. The Holy Spirit will convict someone of their sin when they see you walking in faith and response to God. It is so simple. Be salty, it makes people thirsty.
These "science" so-called debates can be very unprofitable because scientists themselves do not even know what they know 90% of the time. Their theories change every ten years. So when Christians use flawed scientific reasoning to verify truth, you have done truth a disservice. If you want proof of changing theory, read this article.
http://www.technologyreview.com/blog/arxiv/25492/
A theoretical physicist in Taiwan is demolishing the big bang theory and stating that the universe is now to be understood as infinite in scope. It sounds as if his views are gaining traction.
When it comes to math, and scientific theory, people are all over the map. So to rely on an understanding like that is to rely on shifting sands literally.
Giggles is right though, understanding the second law of thermodynamics is a "bit" of a help, just make sure you understand it well before you use it. I have heard Christians attempt to use it, but it turned out they really did not understand it all that well. So others were able to pick loopholes out of their arguments.
The reason that the second law is an exception to the rule is because it is a Law. It is not theory.