It is always sad to hear of a sinner dying in sin. I think of Hebrews 2, "If every transgression and disobedience received a just recompense of reward... how shall we escape if we neglect so great salvation." I recall hearing this earlier in the year as I had listened to some of his debates. Two observations:
1. smoking, for some reason, so I am told gives the smoker a sense that everything is going to be 'all right' when they light up. I was with a dying woman once that had not eaten in over a week and had not drank any liquids in as long. She lived on an IV in her body. When she arose from her bed she did not ask for food or water, but a cigarette. She died a few days later.
2. "alcohol gives a sense of escape from a life that the person dies not like." That is a direct quote from a friend who borders on alcoholism.
That said, the man medicated himself in order to entertain his world view. These things were substitutions for God. We have an interesting passage in Hosea 3:1. Then said the LORD unto me, Go yet, love a woman beloved of [her] friend, yet an adulteress, according to the love of the LORD toward the children of Israel, who look to other gods, and love flagons of wine.
They were taking the love that belonged to God and giving it to other gods and then He singles one out, 'they love flagons of wine.' There is no new thing under the sun. Wine is a mocker and it corrupts judgment in those that are deceived thereby. Once the pain of the cancer came and the heavy meds for soothing it were administered, unless God granted respite, he never had a sober moment to the end. Today if we hear His voice we must not harden our hearts. It's too late for him, but there is still hope for the living.